Niveles de interleuquina 1 beta en el fluido crevicular gingival durante el movimiento dentario en el paciente ortodóncico adulto

Abstract

Periodontal tissue is actively involved in dental movement besides the tooth itself; certain biochemical factors related to bone resorption and formation during orthodontic movement appear in the gingival crevicular fluid.The aim of this study was to appraise the levels of interleukin IL-1β in the crevicular fluid in order to know the inflammatory process that occurs during orthodontic movement and to learn whether or not it may be associated with the pain perceived by patients during treatment.Twenty-nine adult patients (15 women, with an average age of 21.8 ± 1.2 years and 14 men, with an average age of 21.2 ± 1.5 years) were selected to be treated orthodontically by fixed-devices multibrackets. Brackets (0.022 x 0.028 inches, Mini Master, American Orthodontics, Sheboygan, WI, USA, MBT technique) were cemented into the vestibular side of the experimental teeth. A direct cementing tube was cemented into the upper first molar on the same side of the experimental tooth. A 100 g continuous force was applied by means of a Nikon-Titanium coil spring GAC Sentalloy 100 g Closed Coil Springs (GAC International Inc, Bohemia, NY, USA). Crevicular fluid samples were collected in mesial (tension) and distal (compression) of the experimental tooth and distal of the control tooth prior to the application of the orthodontic force, 24 hours later, and 7 and 28 days after applying such force...