Clobetasol Propionato en el tratamiento de la psoriasis en placas

  1. FELIZ, Beatriz
  2. MUSICCO, Felice 1
  3. ALVAREZ, Raquel 2
  1. 1 Instituto Fisioterapéutico hospitalario IFO, Roma
  2. 2 Universidad de Salamanca
    info

    Universidad de Salamanca

    Salamanca, España

    ROR https://ror.org/02f40zc51

Journal:
Farmajournal

ISSN: 2445-1355

Year of publication: 2017

Volume: 2

Issue: 1

Pages: 111-120

Type: Article

More publications in: Farmajournal

Abstract

Psoriasis is a common chronic disease with significant impairment in quality of life. As there is no cure, it often requires lifelong disease control to minimize the development of skin lesions and to relieve symptoms.Psoriasis vulgaris, also called mild / moderate, is a type of psoriasis characterized by manifest localized involvement of a skin surface <10%. For this type of psoriasis, clinical studies have shown increased efficiency based on a combination treatment of topical corticosteroids class I (betamethasone dipropionate) 0.05% with salicylic acid 2-3%, unique in the market.The aim of this study was the preparation of a master formula that combines clobetasol 0.015% incorporated into salicylic vaseline 6% (for non-hirsute area) and sweet al.mond oil with salicylic acid 6% (for the hirsute area) due to the absence of a preparation to ensure the prescribed concentrations and test the effectiveness of this preparation in a sample of patients with mild / moderate psoriasis who come to the hospital through PASI and IGA indexes.

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