Insuficiencia renal aguda experimental por aminoglucosidosefecto sobre el metabolismo fosfocalcico

  1. Diez Prieto, I.
  2. Perez Garcia, C.C.
  3. Rejas Lopez, J.
  4. Alonso Diez, A.J.
  5. Garcia Partida, P.
Revista:
Revista de toxicología

ISSN: 0212-7113

Año de publicación: 1990

Volumen: 7

Número: 1

Páginas: 5-12

Tipo: Artículo

Otras publicaciones en: Revista de toxicología

Resumen

We have evaluated the effect of the nephrotoxic acute renal failure (neomycin sulphate, 100 mg/kg bodyweight) on the calcium and phosphorus metabolism. We have found higher levéisin urea (1,33 g/i), increatinine (7,97 mg/dl), and serical phosphorus (14,43 mg/dl); we have also noticed some increases (though lower) in magnesemia (2,75 mg/dl), in proteinemia (7,15 g/l) and in the activity of alkaline phosphatase (71,25 Ul/I); the calcemia, onthe contrary, hada remarkable decrease (7,81 mg/dl), similar at the hydroxyprolinuria (15,75mg/24 h) but without stadistíc significance, in this case.