Derrame pericárdico postparto, toxicidad pleuropulmonar precoz asociada a carbegolina
- Cantos, C.
- Arnal Burró, Ana María
- Muñoz, A. M.
- García-Serna, I.
- Moreno Reviriego, Ana
- Martín, E.M.
ISSN: 1139-8264
Year of publication: 2012
Volume: 15
Issue: 2
Pages: 81-83
Type: Article
More publications in: Revista española de investigaciones quirúrgicas
Abstract
In order to inhibit lactation in women during the puerperal phase, a single, oral dose of cabergoline is administered. The cabergoline is a long-acting selective dopamine agonist. It inhibits the prolactin synthesis by direct stimulation of D2 receptor in pituitary lactotrophs in a dose dependent. Most of its adverse reactions are slight. Most commonly, this treatment causes only mild side effects, however, cabergoline can also cause severe side effects including valvulopathy and cardiopulmonary fibrotic reactions. These severe adverse reactions are predominantly observed in patients which are given high daily doses of the drug over a prolonged period of time, as is usual in the treatment of illnesses such as hyperprolactinaemia or Parkinson´s disease. We present a case of pericardial effusion and bilateral pleural effusion in a patient during the puerperium, after being treated with two single low-dose cabergoline tablets to inhibit lactation.