Vacunación frente a paratuberculosis en un rebaño caprino a diferentesedades. Estudio de la respuesta inmune periférica
- Royo, M.
- Fuertes, M.
- Fernández, M.
- Castaño, P.
- Manga-González, Y.
- Ferreras, M.C.
- Benavides, J.
- Pérez, V.
- María Jesús Alcalde Aldea (coord.)
- Martín Rodríguez García (coord.)
Publisher: Universitat Politècnica de València
ISBN: 978-84-9048-398-5
Year of publication: 2015
Pages: 456-462
Congress: Sociedad Española de Ovinotecnia y Caprinotecnia (SEOC). Jornadas (11. 2015. Castellón)
Type: Conference paper
Abstract
Vaccination against paratuberculosis has been performed in threegroups of animals (1,5 month-old, 5 month-old and adults) from adairy goat flock. The objective was to assess the peripheral immuneresponse related to vaccination, its effect on the animal losses and themeasurement of the IFN-γ response against different antigens from M.bovis in vaccinated animals. Vaccination induced an intense cellularperipheral immune response that reached the highest level at 6 mpv. Itwas higher in the 5-month-old group than in the rest, and showed thelowest values in the adult group. Although vaccinated animals reactedagainst bovine PPD and PC-HP M. bovis antigens, the response was moreintense to avian PPD or johnin; the latter showed the highest values. Noreaction was detected against PC-ED antigen, suggesting its usefulness inthe differentiation of Map vaccinated and tuberculosis-infected animals.The percentage of losses was lower in vaccinated groups, regardless theage. This fact would indicate that paratuberculosis vaccination couldhave a general beneficial effect.