La investigación clínica en vacunasEl futuro

Resumen

The field of infectious diseases includes vaccines against bacteria, viruses, fungi and parasites, which employ various strategies and production techniques. They are aimed at the identification of new protective antigens (reverse vaccinology, structural vaccinology and immunommunology), the acquisition or enhancement of immunogenicity (vaccination, system vaccinology) and the use of new adjuvants and delivery modalities, heterologous vaccination, conjugation from polysaccharides to proteins and the adversomic. Among the innovative administration routes: the digestive, mucous, and transcutaneous. And as new types of vaccines: recombinants (with or without vectors), nucleic acids, peptide, attenuated and molecularly inactivated, rearranged viruses (rearranged) and adapted to cold. The criteria that should prevail in order to implement "useful" vaccination strategies in our environment must assess the economic and social impact of prevention programs.