Fractal Dimension of the EEG in Alzheimer's Disease

  1. Abásolo, Daniel 1
  2. Escudero, Javier 1
  3. Hornero, Roberto 1
  4. Espino, Pedro 2
  5. Gómez, Carlos 1
  1. 1 Universidad de Valladolid
    info

    Universidad de Valladolid

    Valladolid, España

    ROR https://ror.org/01fvbaw18

  2. 2 Hospital Clínico San Carlos de Madrid
    info

    Hospital Clínico San Carlos de Madrid

    Madrid, España

    ROR https://ror.org/04d0ybj29

Libro:
Encyclopedia of Healthcare Information Systems

Ano de publicación: 2008

Páxinas: 603-609

Tipo: Capítulo de libro

DOI: 10.4018/978-1-59904-889-5.CH076 GOOGLE SCHOLAR lock_openAcceso aberto editor

Obxectivos de Desenvolvemento Sustentable

Resumo

Alzheimer’s disease (AD) is the most frequent cause of dementia in western countries, and is characterized by progressive impairments in cognition and memory, whose course lasts several years prior to death (Jeong, 2004). These clinical features are accompanied by histological changes in the brain, which include widespread cortical atrophy, intracellular deposition of neurofibrillary tangles, and extracellular deposition of senile plaques, particularly in the hippocampus and the cerebral cortex. Although a definite diagnosis is only possible by necropsy, a differential diagnosis with other types of dementia and with major depression should be attempted. Magnetic resonance imaging and computerized tomography can be normal in the early stages of AD, but a diffuse cortical atrophy is the main sign in brain scans. Mental status tests are also useful.