Neurons, Connections, and Microcircuits of the Inferior Colliculus

  1. Ito, Tetsufumi 1
  2. Malmierca, Manuel S. 234
  1. 1 Kanazawa University
    info

    Kanazawa University

    Kanazawa, Japón

    ROR https://ror.org/02hwp6a56

  2. 2 Instituto de Neurociencias de Castilla y León
    info

    Instituto de Neurociencias de Castilla y León

    Salamanca, España

  3. 3 Universidad de Salamanca
    info

    Universidad de Salamanca

    Salamanca, España

    ROR https://ror.org/02f40zc51

  4. 4 Instituto de Investigación Biomédica de Salamanca
    info

    Instituto de Investigación Biomédica de Salamanca

    Salamanca, España

    ROR https://ror.org/03em6xj44

Show affiliations +
Book:
The Mammalian Auditory Pathways: Synaptic Organization and Microcircuits

Publisher: Springer

ISSN: 0947-2657,  2197-1897

ISBN: 9783319717968,  9783319717982

Year of publication: 2018

Pages: 127-167

Type: Book chapter

DOI: 10.1007/978-3-319-71798-2_6 GOOGLE SCHOLAR lock_openOpen access editor

Abstract

In this chapter, the neural circuitry of the inferior colliculus (IC) is described at a cellular level. The IC is subdivided into the central nucleus (ICC) and surrounding cortices that receive specific combinations of inputs and generate diverse outputs. Neuronal types in the IC can be distinguished by their dendritic arborization patterns, neurochemical profiles, and physiological properties. Based on these properties, neuronal types organizing the ICC appear to be different from those organizing the IC cortex. The IC receives ascending inputs from the cochlear nuclei, superior olivary complex, and nuclei of the lateral lemniscus, and the IC receives descending inputs from the auditory cortex and nonauditory inputs from various nuclei. Each input source forms terminal fields in particular zones of the IC. Massive commissural and local inputs are also present. One well-characterized cell type, the large GABAergic IC neuron, receives convergent input from all of these sources. The IC neurons project to the auditory thalamus as well as to lower brain stem nuclei. Anatomical and physiological features suggest that ICC acts as an auditory integration center, and IC cortex acts as a multimodal integration center and novelty detector. These data support the view that the lemniscal and nonlemniscal pathways emerge at the midbrain level.

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