Synthesis and characterization of Ru(II), Ir(III) and Rh(III) trischelate complexes with benzimidazole based ligands for photodynamic therapy and photocatalysishe bright side of the chemistry

Résumé

The following thesis details the research work carried out in the synthesis and characterization of tris-chelate compounds of Ru(II), Ir(III) and Rh(III) with ligands based on benzimidazoles, for use in two fields, photodynamic therapy or PDT, and photocatalysis. The election of these metals and ligands has been made due to their well-known pharmacological and photophysical properties, which makes them an interesting option for both fields of application. It is worth highlighting the interest of these areas of study, being PDT an anticancer therapy with the advantages of allowing an accurate space-time control and inhibiting the drug resistance mechanisms often presented by the cancer cells. And the photocatalysis, a variant of traditional catalysis that uses visible light as an energy source, making possible to carry out reactions in mild and environmentally benign conditions.