INGENIERÍA METABÓLICA
Centro de Investigaciones Biológicas
Madrid, EspañaPublikationen in Zusammenarbeit mit Forschern von Centro de Investigaciones Biológicas (24)
2021
2020
2019
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A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity
Journal of Molecular Biology, Vol. 431, Núm. 5, pp. 956-969
2017
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Deciphering how Cpl-7 cell wall-binding repeats recognize the bacterial peptidoglycan
Scientific Reports, Vol. 7, Núm. 1
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Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine
PLoS Neglected Tropical Diseases, Vol. 11, Núm. 8
2016
2012
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Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, Vol. 8, Núm. 4, pp. 445-544
2010
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Mapping flexibility and the assembly switch of cell division protein FtsZ by computational and mutational approaches
Journal of Biological Chemistry, Vol. 285, Núm. 29, pp. 22554-22565
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Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity
ChemBioChem, Vol. 11, Núm. 12, pp. 1669-1678
2009
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Protein shape and assembly studied with X-ray solution scattering: Fundaments and practice
Lecture Notes in Physics, Vol. 776, pp. 245-263
2008
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Apo-Hsp90 coexists in two open conformational states in solution
Biology of the Cell, Vol. 100, Núm. 7, pp. 413-425
2007
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Characterizing ligand-microtubule binding by competition methods.
Methods in molecular medicine, Vol. 137, pp. 245-260
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Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites
Nature Chemical Biology, Vol. 3, Núm. 2, pp. 117-125
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Insights into Molecular Plasticity of Choline Binding Proteins (Pneumococcal Surface Proteins) by SAXS
Journal of Molecular Biology, Vol. 365, Núm. 2, pp. 411-424
2006
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Farnesyltransferase inhibitors reverse taxane resistance
Cancer Research, Vol. 66, Núm. 17, pp. 8838-8846
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NMR determination of the bioactive conformation of Peloruside A bound to microtubules
Journal of the American Chemical Society, Vol. 128, Núm. 27, pp. 8757-8765
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The nucleotide switch of tubulin and microtubule assembly: A polymerization-driven structural change
Biochemistry, Vol. 45, Núm. 19, pp. 5933-5938
2005
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Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site
Biochemistry, Vol. 44, Núm. 34, pp. 11525-11538
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Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: Modification of the side chain
Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 9, pp. 2243-2247