GENÉTICA MOLECULAR EN ONCOHEMATOLOGÍA
Hospital Infanta Leonor
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Hospital Infanta Leonor (18)
2024
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Chronic lymphocytic leukemia patients with chromosome 6q deletion as the sole cytogenetic abnormality display a high frequency of RPS15 mutations and have a poor prognosis
American Journal of Hematology
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Low dose lenalidomide versus placebo in non-transfusion dependent patients with low risk, del(5q) myelodysplastic syndromes (SintraREV): a randomised, double-blind, phase 3 trial
The Lancet Haematology, Vol. 11, Núm. 9, pp. e659-e670
2022
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TRAF3 alterations are frequent in del-3′IGH chronic lymphocytic leukemia patients and define a specific subgroup with adverse clinical features
American Journal of Hematology, Vol. 97, Núm. 7, pp. 903-914
2021
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Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression
Blood Cancer Journal, Vol. 11, Núm. 7
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The evolving landscape of chronic lymphocytic leukemia on diagnosis, prognosis and treatment
Diagnostics, Vol. 11, Núm. 5
2020
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Chronic lymphocytic leukemia patients with IGH translocations are characterized by a distinct genetic landscape with prognostic implications
International Journal of Cancer, Vol. 147, Núm. 10, pp. 2780-2792
2019
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DNA damage response-related alterations define the genetic background of patients with chronic lymphocytic leukemia and chromosomal gains
Experimental Hematology, Vol. 72, pp. 9-13
2018
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Characterizing patients with multiple chromosomal aberrations detected by FISH in chronic lymphocytic leukemia
Leukemia and Lymphoma, Vol. 59, Núm. 3, pp. 633-642
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The International Prognostic Index for Patients with Chronic Lymphocytic Leukemia Has the Higher Value in Predicting Overall Outcome Compared with the Barcelona-Brno Biomarkers only Prognostic Model and the MD Anderson Cancer Center Prognostic Index
BioMed Research International, Vol. 2018
2017
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Hyperdiploidy as a rare event that accompanies poor prognosis markers in CLL
European Journal of Haematology, Vol. 98, Núm. 2, pp. 142-148
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Next-generation sequencing and FISH studies reveal the appearance of gene mutations and chromosomal abnormalities in hematopoietic progenitors in chronic lymphocytic leukemia
Journal of Hematology and Oncology, Vol. 10, Núm. 1
2016
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A high proportion of cells carrying trisomy 12 is associated with a worse outcome in patients with chronic lymphocytic leukemia
Hematological Oncology, Vol. 34, Núm. 2, pp. 84-92
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MiRNA expression profile of chronic lymphocytic leukemia patients with 13q deletion
Leukemia Research, Vol. 46, pp. 30-36
2015
2014
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Interstitial 13q14 deletions detected in the karyotype and translocations with concomitant deletion at 13q14 in chronic lymphocytic leukemia: Different genetic mechanisms but equivalent poorer clinical outcome
Genes Chromosomes and Cancer, Vol. 53, Núm. 9, pp. 788-797
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Mutation status and immunoglobulin gene rearrangements in patients from northwest and central region of Spain with chronic lymphocytic leukemia
BioMed Research International, Vol. 2014