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DISEÑO, SINTESIS Y EVALUACIÓN DE AGENTES ANTITUMORALES
Publicacions (41) Publicacions en què ha participat algun/a investigador/a
2024
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Current drug strategies for the treatment and control of schistosomiasis
Expert Opinion on Pharmacotherapy, Vol. 25, Núm. 4, pp. 409-420
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Deciphering Chemical Rules for Drug Penetration into Strongyloides
Pharmaceutics, Vol. 16, Núm. 9
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Editorial: Pharmacoinformatics: new developments and challenges in drug design
Frontiers in Pharmacology
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Experimental structure based drug design (SBDD) applications for anti-leishmanial drugs: A paradigm shift?
Medicinal Research Reviews, Vol. 44, Núm. 3, pp. 1055-1120
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Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents
European Journal of Medicinal Chemistry, Vol. 275
2023
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Frentizole, a Nontoxic Immunosuppressive Drug, and Its Analogs Display Antitumor Activity via Tubulin Inhibition
International Journal of Molecular Sciences, Vol. 24, Núm. 24
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GuaB3, an overlooked enzyme in cyanobacteria's toolbox that sheds light on IMP dehydrogenase evolution
Structure, Vol. 31, Núm. 12, pp. 1526-1534.e4
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Novel Tetrazole Derivatives Targeting Tubulin Endowed with Antiproliferative Activity against Glioblastoma Cells
International Journal of Molecular Sciences, Vol. 24, Núm. 13
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Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy
Bioorganic Chemistry, Vol. 131
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Nuevos antitumorales y antiparasitarios de naturaleza híbrida para la formación de nanopartículas
IX Jornadas de investigadoras de Castilla y León
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Potent and Selective Benzothiazole-Based Antimitotics with Improved Water Solubility: Design, Synthesis, and Evaluation as Novel Anticancer Agents
Pharmaceutics, Vol. 15, Núm. 6
2022
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Modelo in vitro para evaluar la actividad de compuestos antiparasitarios frente a Trichinella spiralis
XII Congreso de la Sociedad Española de Medicina Tropical y Salud Internacional (SEMTSI)
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Panobinostat Synergistically Enhances the Cytotoxicity of Microtubule Destabilizing Drugs in Ovarian Cancer Cells
International Journal of Molecular Sciences, Vol. 23, Núm. 21
2021
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Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues
European Journal of Medicinal Chemistry, Vol. 223
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Application of ensemble pharmacophore-based virtual screening to the discovery of novel antimitotic tubulin inhibitors
Computational and Structural Biotechnology Journal, Vol. 19, pp. 4360-4372
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Implementación y virtualización de las Jornadas de Inicio de las Prácticas Tuteladas del Grado en Farmacia
XVI Symposium Internacional sobre el Practicum y las prácticas externas. Prácticas externas virtuales versus presenciales: transformando los retos en oportunidades para la innovación: actas. Poio (Pontevedra) 7, 8 y 9 de julio de 2021
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Methoxy and bromo scans on N-(5-methoxyphenyl) methoxybenzenesulphonamides reveal potent cytotoxic compounds, especially against the human breast adenocarcinoma MCF7 cell line
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 1029-1047
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Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents
European Journal of Medicinal Chemistry, Vol. 209
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Microtubule destabilizing sulfonamides as an alternative to taxane-based chemotherapy
International Journal of Molecular Sciences, Vol. 22, Núm. 4, pp. 1-21
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New diarylsulfonamide inhibitors of Leishmania infantum amastigotes
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 16, pp. 45-64