GTPASAS Y CÁNCER: SEÑALIZACIÓN MEDIADA POR RAS
Publicaciones (38) Publicaciones en las que ha participado algún/a investigador/a
2024
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Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice
Cell Communication and Signaling, Vol. 22, Núm. 1
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Randomised, double-blind, placebo-controlled, parallel-group, multicentric, phase IIA clinical trial for evaluating the safety, tolerability, and therapeutic efficacy of daily oral administration of NFX88 to treat neuropathic pain in individuals with spinal cord injury
Spinal Cord, Vol. 62, Núm. 8, pp. 454-467
2023
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Advances in Molecular Research of Oncogenes
International Journal of Molecular Sciences
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
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Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma
Nature Communications, Vol. 14, Núm. 1
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GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina
Cells, Vol. 12, Núm. 21
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Optimized Protocol for Isolation and Culture of Murine Neonatal Primary Lung Fibroblasts
Methods and Protocols, Vol. 6, Núm. 1
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PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability
Oncogenesis, Vol. 12, Núm. 1
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Unveiling the Mysteries of RAS Signaling: A Journey of Discovery and Breakthroughs
Genes
2022
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Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia
Cancers, Vol. 14, Núm. 16
2021
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40 years of RAS-a historic overview
Genes, Vol. 12, Núm. 5
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Anthraquinones as inhibitors of SOS RAS-GEF activity
Biomolecules, Vol. 11, Núm. 8
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Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis
Oncogene, Vol. 40, Núm. 27, pp. 4538-4551
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Functional specificity of the members of the sos family of ras‐gef activators: Novel role of sos2 in control of epidermal stem cell homeostasis
Cancers, Vol. 13, Núm. 9
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Ras GEF Mouse Models for the Analysis of Ras Biology and Signaling
Methods in Molecular Biology (Humana Press Inc.), pp. 361-395
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Sos2 comes to the fore: Differential functionalities in physiology and pathology
International Journal of Molecular Sciences, Vol. 22, Núm. 12
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The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction
Genes, Vol. 12, Núm. 6
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The childhood-onset neurodegeneration with cerebellar atrophy (Condca) disease caused by agtpbp1 gene mutations: The purkinje cell degeneration mouse as an animal model for the study of this human disease
Biomedicines, Vol. 9, Núm. 9
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The importance of being PI3K in the RAS signaling network
Genes, Vol. 12, Núm. 7
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The reversed intra- and extracellular pH in tumors as a unified strategy to chemotherapeutic delivery using targeted nanocarriers
Acta Pharmaceutica Sinica B, Vol. 11, Núm. 8, pp. 2243-2264