APLICACIONES BIOTECNOLÓGICAS DE ACTINOBACTERIAS
BIOACTINOTEC
Paloma
Liras Padín
Publicaciones en las que colabora con Paloma Liras Padín (15)
2019
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Activation of secondary metabolite gene clusters in streptomyces clavuligerusby the pimm regulator of streptomyces natalensis
Frontiers in Microbiology, Vol. 10, Núm. MAR
1998
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The nine genes of the Nocardia lactamdurans cephamycin cluster are transcribed into large mRNAs from three promoters, two of them located in a bidirectional promoter region
Journal of Bacteriology, Vol. 180, Núm. 20, pp. 5489-5494
1997
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The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A β-lactamase of low enzymatic activity
Journal of Bacteriology, Vol. 179, Núm. 19, pp. 6035-6040
1996
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Characterization of the cefF gene of Nocardia lactamdurans encoding a 3′-methylcephem hydroxylase different from the 7-cephem hydroxylase
Applied Microbiology and Biotechnology, Vol. 44, Núm. 5, pp. 605-609
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Overexpression of the Nocardia lactamdurans α-aminoadipyl-cysteinyl-valine synthetase in Streptomyces lividans. The purified multienzyme uses cystathionine and 6-oxopiperidine 2-carboxylate as substrates for synthesis of the tripeptide
European Journal of Biochemistry, Vol. 242, Núm. 2, pp. 264-270
1995
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A two-protein component 7α-cephem-methoxylase encoded by two genes of the cephamycin C cluster converts cephalosporin C to 7-methoxycephalosporin C
Journal of Bacteriology, Vol. 177, Núm. 8, pp. 2230-2235
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Characterization of the cmcH genes of Nocardia lactamdurans and streptomyces clavuligerus encoding a functional 3'-hydroxymethylcephem O-carbamoyltransferase for cephamycin biosynthesis
Gene, Vol. 162, Núm. 1, pp. 21-27
1994
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Grouping of the genes of biosynthesis and resistance to beta-lactam antibiotics in cephamycin-C producing actinomycetes
Microbiología (Madrid, Spain), Vol. 10, Núm. 1-2, pp. 49-56
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Interdependence of Gene Expression for Early Steps of Cephalosporin Synthesis in Streptomyces clavuligerus
Annals of the New York Academy of Sciences, Vol. 721, Núm. 1, pp. 117-122
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Possible involvement of the lysine ε-aminotransferase gene (lat) in the expression of the genes encoding ACV synthetase (pcbAB) and isopenicillin N synthase (pcbC) in Streptomyces clavuligerus
Microbiology, Vol. 140, Núm. 12, pp. 3367-3377
1993
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Analysis of the codon usage of the cephamycin C producer Nocardia lactamdurans
FEMS Microbiology Letters, Vol. 110, Núm. 1, pp. 91-95
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Characterization and expression in Streptomyces lividans of cefD and cefE genes from Nocardia lactamdurans: the organization of the cephamycin gene cluster differs from that in Streptomyces clavuligerus
MGG Molecular & General Genetics, Vol. 236, Núm. 2-3, pp. 453-458
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Genes for a β-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans
EMBO Journal, Vol. 12, Núm. 2, pp. 631-639
1991
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A gene encoding lysine 6-aminotransferase, which forms the β-lactam precursor α-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans
Journal of Bacteriology, Vol. 173, Núm. 19, pp. 6258-6264
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The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum
Molecular Microbiology, Vol. 5, Núm. 5, pp. 1125-1133