Iker
Uriarte Diaz Varela
Publicaciones en las que colabora con Iker Uriarte Diaz Varela (15)
2024
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Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Gut
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New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1870, Núm. 5
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Non-mitogenic FGF19 mRNA-based therapy for the treatment of experimental metabolic dysfunction-associated steatotic liver disease (MASLD)
Clinical science (London, England : 1979), Vol. 138, Núm. 20, pp. 1265-1284
2023
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Identification and experimental validation of druggable epigenetic targets in hepatoblastoma
Journal of Hepatology, Vol. 79, Núm. 4, pp. 989-1005
2022
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New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
Journal of Experimental and Clinical Cancer Research, Vol. 41, Núm. 1
2021
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis
Molecular Therapy - Methods and Clinical Development, Vol. 22, pp. 210-221
2020
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Dual pharmacological targeting of hdacs and pde5 inhibits liver disease progression in a mouse model of biliary inflammation and fibrosis
Cancers, Vol. 12, Núm. 12, pp. 1-27
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Pilot multi-omic analysis of human bile from benign and malignant biliary strictures: A machine-learning approach
Cancers, Vol. 12, Núm. 6, pp. 1-30
2019
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The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis
Hepatology, Vol. 69, Núm. 4, pp. 1632-1647
2018
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Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1864, Núm. 9, pp. 2927-2937
2014
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A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver
Gastroenterology, Vol. 147, Núm. 5, pp. 1084-1093
2013
2012
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Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice
Journal of Hepatology, Vol. 56, Núm. 2, pp. 367-373
2010
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Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat
Hepatology, Vol. 52, Núm. 2, pp. 667-677