Publicaciones en las que colabora con Mariano Barbacid Montalbán (22)

2021

  1. RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression

    Cancer Cell

2020

  1. Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma

    JCI Insight, Vol. 5, Núm. 15

  2. Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Núm. 39, pp. 24415-24426

2019

  1. Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27

    Scientific Reports, Vol. 9, Núm. 1

2017

  1. A Braf kinase-inactive mutant induces lung adenocarcinoma

    Nature, Vol. 548, Núm. 7666, pp. 239-243

  2. In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma

    Oncogene, Vol. 36, Núm. 16, pp. 2309-2318

2016

  1. Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma

    Nature Medicine, Vol. 22, Núm. 3, pp. 270-277

  2. KRAS-driven lung adenocarcinoma: Combined DDR1/Notch inhibition as an effective therapy

    ESMO Open, Vol. 1, Núm. 5

2015

  1. Functional Reprogramming of Polyploidization in Megakaryocytes

    Developmental Cell, Vol. 32, Núm. 2, pp. 155-167

2014

  1. Genetic characterization of the role of the Cip/Kip family of proteins as cyclin-dependent kinase inhibitors and assembly factors

    Molecular and Cellular Biology, Vol. 34, Núm. 8, pp. 1452-1459

  2. Lentiviral-based approach for the validation of cancer therapeutic targets in vivo

    BioTechniques, Vol. 57, Núm. 4, pp. 179-187

  3. Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts

    Cancer Research, Vol. 74, Núm. 21, pp. 5978-5988

2012

  1. Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion

    EMBO Journal, Vol. 31, Núm. 11, pp. 2498-2510

2011

  1. C-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma

    Cancer Cell, Vol. 19, Núm. 5, pp. 652-663

  2. Cdk6-dependent regulation of G1 length controls adult neurogenesis

    Stem Cells, Vol. 29, Núm. 4, pp. 713-724

  3. Toll-like receptor-4 (TLR4) down-regulates microRNA-107, increasing macrophage adhesion via cyclin-dependent kinase 6

    Journal of Biological Chemistry, Vol. 286, Núm. 29, pp. 25531-25539

2010

  1. A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma

    Cancer Cell, Vol. 18, Núm. 1, pp. 63-73

2009

  1. Overall Cdk activity modulates the DNA damage response in mammalian cells

    Journal of Cell Biology, Vol. 187, Núm. 6, pp. 773-780

2007

  1. Cdk1 is sufficient to drive the mammalian cell cycle

    Nature, Vol. 448, Núm. 7155, pp. 811-815

  2. Mice thrive without Cdk4 and Cdk2

    Molecular Oncology, Vol. 1, Núm. 1, pp. 72-83