David
Santamaría Velilla
Centro Nacional de Investigaciones Oncológicas
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro Nacional de Investigaciones Oncológicas (29)
2024
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Type I interferon signaling pathway enhances immune-checkpoint inhibition in KRAS mutant lung tumors
Proceedings of the National Academy of Sciences of the United States of America, Vol. 121, Núm. 36
2020
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Inhibition of DDR1 enhances in vivo chemosensitivity in KRAS-mutant lung adenocarcinoma
JCI Insight, Vol. 5, Núm. 15
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Squamous differentiation requires G2/mitosis slippage to avoid apoptosis
Cell Death and Differentiation, Vol. 27, Núm. 8, pp. 2451-2467
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Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Núm. 39, pp. 24415-24426
2019
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Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27
Scientific Reports, Vol. 9, Núm. 1
2017
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A Braf kinase-inactive mutant induces lung adenocarcinoma
Nature, Vol. 548, Núm. 7666, pp. 239-243
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In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma
Oncogene, Vol. 36, Núm. 16, pp. 2309-2318
2016
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An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia
Oncotarget, Vol. 7, Núm. 32, pp. 51163-51173
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Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma
Nature Medicine, Vol. 22, Núm. 3, pp. 270-277
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KRAS-driven lung adenocarcinoma: Combined DDR1/Notch inhibition as an effective therapy
ESMO Open, Vol. 1, Núm. 5
2015
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CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase
Journal of Cell Science, Vol. 128, Núm. 1, pp. 88-99
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Functional Reprogramming of Polyploidization in Megakaryocytes
Developmental Cell, Vol. 32, Núm. 2, pp. 155-167
2014
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Genetic characterization of the role of the Cip/Kip family of proteins as cyclin-dependent kinase inhibitors and assembly factors
Molecular and Cellular Biology, Vol. 34, Núm. 8, pp. 1452-1459
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Lentiviral-based approach for the validation of cancer therapeutic targets in vivo
BioTechniques, Vol. 57, Núm. 4, pp. 179-187
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Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts
Cancer Research, Vol. 74, Núm. 21, pp. 5978-5988
2012
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Cdk7: Open questions beyond the prevailing model
Cell Cycle
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Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion
EMBO Journal, Vol. 31, Núm. 11, pp. 2498-2510
2011
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C-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma
Cancer Cell, Vol. 19, Núm. 5, pp. 652-663
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Cdk6-dependent regulation of G1 length controls adult neurogenesis
Stem Cells, Vol. 29, Núm. 4, pp. 713-724