Publikationen in Zusammenarbeit mit Forschern von National Cancer Institute (34)

2013

  1. Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival

    Molecular and Cellular Biology, Vol. 33, Núm. 22, pp. 4562-4578

2000

  1. The Sos1 and Sos2 Ras-specific exchange factors: Differences in placental expression and signaling properties

    EMBO Journal, Vol. 19, Núm. 4, pp. 642-654

  2. The isoform-specific stretch of hSos1 defines a new Grb2-binding domain

    Oncogene, Vol. 19, Núm. 51, pp. 5872-5883

1999

  1. Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1

    Oncogene, Vol. 18, Núm. 9, pp. 1651-1661

  2. Oncogenic Ras-induced germinal vesicle breakdown is independent of phosphatidylinositol 3-kinase in Xenopus oocytes

    FEBS Letters, Vol. 451, Núm. 3, pp. 284-288

1998

  1. Transformation suppressor activity of C3G is independent of its CDC25-homology domain

    Oncogene, Vol. 16, Núm. 5, pp. 613-624

  2. Transforming G protein-coupled receptors block insulin and ras-induced adipocytic differentiation in 3T3-L1 cells: Evidence for a PKC and MAP kinase independent pathway

    Biochemical and Biophysical Research Communications, Vol. 245, Núm. 2, pp. 554-561

1997

  1. Biological activity of p27(kip1) and its amino- and carboxy-terminal domains in G2/M transition of Xenopus oocytes

    Oncogene, Vol. 15, Núm. 21, pp. 2541-2551

  2. Carboxyl-terminal domain of p27(Kip1) activates CDC2

    Journal of Biological Chemistry, Vol. 272, Núm. 35, pp. 21669-21672

  3. Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation

    Molecular and Cellular Biology, Vol. 17, Núm. 10, pp. 6068-6075

1996

  1. A 15 amino acid stretch close to the Grb2-binding domain defines two differentially expressed hSos1 isoforms with markedly different Grb2 binding affinity and biological activity

    Oncogene, Vol. 12, Núm. 11, pp. 2291-2300

  2. Expression of alternative forms of Ras exchange factors GRF and SOS1 in different human tissues and cell lines

    Oncogene, Vol. 12, Núm. 5, pp. 1097-1107

  3. Functional interactions between isolated SH2 domains and insulin/Ras signaling pathways of Xenopus oocytes: Opposite effects of the carboxy- and amino-terminal SH2 domains of p85 PI 3-kinase

    Oncogene, Vol. 13, Núm. 9, pp. 1839-1846

  4. Isolated Sos1 PH domain exhibits germinal vesicle breakdown-inducing activity in Xenopus oocytes

    Journal of Biological Chemistry, Vol. 271, Núm. 30, pp. 18272-18276

  5. The insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells: Dissociation between Raf-1 kinase and the MAPK/RSK cascade

    International Journal of Obesity

1995

  1. A Divalent Metal Ion Binding Site in the Kinase Insert Domain of the α-Platelet-Derived Growth Factor Receptor Regulates Its Association with SH2 Domains

    Biochemistry, Vol. 34, Núm. 7, pp. 2095-2106

  2. Human dual specificity phosphatase VHR activates maturation promotion factor and triggers meiotic maturation in Xenopus oocytes

    Journal of Biological Chemistry, Vol. 270, Núm. 23, pp. 14229-14234

1994

  1. An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: Evidence for a ret-specific signaling pathway

    Molecular and Cellular Biology, Vol. 14, Núm. 1, pp. 663-675

  2. Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen- activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells

    Journal of Biological Chemistry, Vol. 269, Núm. 17, pp. 12741-12748

1993

  1. P21(ras)-induced meiotic maturation of Xenopus oocytes in the absence of protein synthesis: MPF activation is preceded by activation of MAP and S6 kinases

    Oncogene, Vol. 8, Núm. 2, pp. 467-477