Manuel
Medarde Agustín
Investigador hasta 2021
Publicaciones en las que colabora con María Concepción Pérez Melero (12)
2011
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Synthesis of novel polynitrogenated drugs based on phenstatins. Tubulin polymerization evaluation
4TH EUROPEAN CONFERENCE ON CHEMISTRY FOR LIFE SCIENCES
2010
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Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins
European Journal of Medicinal Chemistry, Vol. 45, Núm. 2, pp. 588-597
2008
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Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 11, pp. 5952-5961
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Naphthylphenstatins as tubulin ligands: Synthesis and biological evaluation
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 19, pp. 8999-9008
2007
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Conformationally restricted macrocyclic analogues of combretastatins
Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 22, pp. 6316-6320
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Synthesis and biological activity of naphthalene analogues of phenstatins: Naphthylphenstatins
Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 12, pp. 3417-3420
2005
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Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety
Journal of Medicinal Chemistry, Vol. 48, Núm. 2, pp. 556-568
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New naphthylcombretastatins. Modifications on the ethylene bridge
Bioorganic and Medicinal Chemistry, Vol. 13, Núm. 6, pp. 2097-2107
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Stilbenophane analogues of deoxycombretastatin A-4
Journal of Organic Chemistry, Vol. 70, Núm. 16, pp. 6544-6547
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Synthesis of a conformationally restricted polyoxygenated crownophane
Tetrahedron Letters, Vol. 46, Núm. 41, pp. 7055-7057
2004
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A new family of quinoline and quinoxaline analogues of combretastatins
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 14, pp. 3771-3774
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Naphthalene combretastatin analogues: Synthesis, cytotoxicity and antitubulin activity
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 19, Núm. 6, pp. 521-540