Manuel
Medarde Agustín
Investigador hasta 2021
Publicaciones en las que colabora con María Pilar Puebla Ibáñez (27)
2019
2018
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Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells
European Journal of Medicinal Chemistry, Vol. 158, pp. 167-183
2016
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Pyridine based antitumour compounds acting at the colchicine site
Current Medicinal Chemistry, Vol. 23, Núm. 11, pp. 1100-1130
2013
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Endowing indole-based tubulin inhibitors with an anchor for derivatization: Highly potent 3-substituted indolephenstatins and indoleisocombretastatins
Journal of Medicinal Chemistry, Vol. 56, Núm. 7, pp. 2813-2827
2008
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Imino-Diels-Alder reactions of 1-aryl-3-(trialkylsiloxy)-1,3-butadienes in solution and the solid phase
European Journal of Organic Chemistry, pp. 4004-4014
2006
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Reactivity of 4-tert-butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with hydrazines
Molecules, Vol. 11, Núm. 11, pp. 929-939
2005
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Diels-Alder reactivity of 4-aryl-1-phthalimido-2-siloxy-1,3-butadienes
Tetrahedron, Vol. 61, Núm. 28, pp. 6871-6878
2004
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1-Phthalimido-4-(3-indolyl)-2-siloxy-1,3-butadienes: Synthesis and Diels-Alder reactivity
Tetrahedron Letters, Vol. 45, Núm. 8, pp. 1631-1634
2003
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Naphthalene analogues of lignans
Journal of Organic Chemistry, Vol. 68, Núm. 3, pp. 854-864
2002
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Synthesis and cytotoxic activities of analogues of thuriferic acid
Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 2, pp. 303-312
2001
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Synthesis of imidazo[4,5-d]oxazolo[3,4-a]pyridines. New heterocyclic analogues of lignans
Archiv der Pharmazie, Vol. 334, Núm. 5, pp. 177-179
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Trypanosoma cruzi: Inhibition of parasite growth and respiration by oxazolo(thiazolo)pyridine derivatives and its relationship to redox potential and lipophilicity
Experimental Parasitology, Vol. 99, Núm. 1, pp. 1-6
2000
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Antihypertensive activity of substituted 2,3,8,8a-tetrahydro-7H-oxazolo[3,2-a]pyridinedicarboxylate enantiomers
Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 4, pp. 319-322
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Effects of 3-chloro-phenyl-1,4-dihydropyridine derivatives on Trypanosome cruzi epimastigotes
Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology, Vol. 125, Núm. 1, pp. 103-109
1999
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A convenient method for the synthesis of six-membered heterocyclic enaminones
Journal of Heterocyclic Chemistry, Vol. 36, Núm. 4, pp. 1097-1099
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Synthesis of fused heterocycles from heterocyclic enaminones
Tetrahedron, Vol. 55, Núm. 25, pp. 7915-7922
1998
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Reactivity of N-substituted enaminones with unsaturated carbonyl compounds
ACH - Models in Chemistry, Vol. 135, Núm. 4, pp. 457-473
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Synthesis of thiazolo[2,3-a]pyridines from enaminoesters by tandem conjugate addition-cyclization
Tetrahedron Letters, Vol. 39, Núm. 5-6, pp. 455-458
1997
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Antihypertensive effect of some oxazolo[3,2-a]pyridines, thiazolo[3,2-a]pyridines and pyrido[2,1-b]oxazines in conscious spontaneously hypertensive rats
Journal of Pharmacy and Pharmacology, Vol. 49, Núm. 4, pp. 421-425
1996
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Enantiospecific synthesis of dihydropyridines from chiral enamines
Tetrahedron Asymmetry, Vol. 7, Núm. 7, pp. 1985-1994