Publicacions (30) Publicacions de Jaime Santo Domingo Mayoral

2023

  1. Measurements of Calcium in Chromaffin Cell Organelles Using Targeted Aequorins

    Methods in molecular biology (Clifton, N.J.), Vol. 2565, pp. 153-177

  2. SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans

    Frontiers in Pharmacology, Vol. 14

  3. SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin-secreting cells

    Journal of Cell Science, Vol. 136, Núm. 8

  4. The mitochondrial calcium uniporter (MCU) activates mitochondrial respiration and enhances mobility by regulating mitochondrial redox state

    Redox Biology, Vol. 64

2022

  1. Mitochondrial respiratory chain dysfunction alters ER sterol sensing and mevalonate pathway activity

    Journal of Biological Chemistry, Vol. 298, Núm. 3

  2. Modeling Alzheimer’s Disease in Caenorhabditis elegans

    Biomedicines, Vol. 10, Núm. 2

2021

  1. Mitochondrial ion channels in pancreatic β-cells: Novel pharmacological targets for the treatment of Type 2 diabetes

    British Journal of Pharmacology, Vol. 178, Núm. 10, pp. 2077-2095

2020

  1. Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

    Diabetologia, Vol. 63, Núm. 12, pp. 2628-2640

  2. Protein Lysine Acetylation: Grease or Sand in the Gears of β-Cell Mitochondria?

    Journal of Molecular Biology, Vol. 432, Núm. 5, pp. 1446-1460

  3. Targeting mitochondrial calcium uptake with the natural flavonol kaempferol, to promote metabolism/secretion coupling in pancreatic β-cells

    Nutrients, Vol. 12, Núm. 2

  4. Targeting mitochondrial ion channels in Type 2 diabetes

    Future Medicinal Chemistry, Vol. 12, Núm. 17, pp. 1525-1527

2019

  1. Cellular stress is a prerequisite for glucose-induced mitochondrial matrix alkalinization in pancreatic β-cells

    Molecular and Cellular Endocrinology, Vol. 481, pp. 71-83

  2. Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cells

    Cell Communication and Signaling, Vol. 17, Núm. 1

  3. Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release from the endoplasmic reticulum by AMP-activated kinase modulators

    Cell Calcium, Vol. 77, pp. 68-76

  4. The plant product quinic acid activates Ca2+-dependent mitochondrial function and promotes insulin secretion from pancreatic beta cells

    British Journal of Pharmacology, Vol. 176, Núm. 17, pp. 3250-3263

2017

  1. A novel ATP-synthase-independent mechanism coupling mitochondrial activation to exocytosis in insulin-secreting cells

    Journal of Cell Science, Vol. 130, Núm. 11, pp. 1929-1939

  2. Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation

    Scientific Reports, Vol. 7

  3. Antibiotics induce mitonuclear protein imbalance but fail to inhibit respiration and nutrient activation in pancreatic β-cells

    Experimental Cell Research, Vol. 357, Núm. 2, pp. 170-180

  4. Coordinated activation of mitochondrial respiration & exocytosis mediated by PKC signaling in pancreatic β cells

    FASEB Journal, Vol. 31, Núm. 3, pp. 1028-1045

  5. Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation

    Scientific reports