Isidro
Sánchez García
Universidad Autónoma de Madrid
Madrid, EspañaPublicacións en colaboración con investigadores/as de Universidad Autónoma de Madrid (28)
2024
2023
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Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice
Nature Communications, Vol. 14, Núm. 1
2022
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Childhood B-Cell Preleukemia Mouse Modeling
International Journal of Molecular Sciences, Vol. 23, Núm. 14
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Revisiting the concept of childhood preleukemia
Trends in Cancer
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Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice
Cancer research, Vol. 82, Núm. 6, pp. 1098-1109
2021
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An immune window of opportunity to prevent childhood B cell leukemia
Trends in Immunology
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Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice
Blood, Vol. 137, Núm. 13, pp. 1741-1753
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Infectious triggers and novel therapeutic opportunities in childhood B cell leukaemia
Nature Reviews Immunology, Vol. 21, Núm. 9, pp. 570-581
2017
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Infection exposure promotes ETV6-RUNX1 precursor B-cell leukemia via impaired H3K4 demethylases
Cancer Research, Vol. 77, Núm. 16, pp. 4365-4377
2016
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GEMMs addressing Pax5 loss-of-function in childhood pB-ALL
European Journal of Medical Genetics, Vol. 59, Núm. 3, pp. 166-172
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Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics
Nature Communications, Vol. 7
2015
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Infection exposure is a causal factor in B-cell precursor acute lymphoblastic leukemia as a result of Pax5-inherited susceptibility
Cancer Discovery, Vol. 5, Núm. 12, pp. 1328-1343
2014
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Genetically engineered mouse models of human B-cell precursor leukemias
Cell Cycle, Vol. 13, Núm. 18, pp. 2836-2846
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Lineage-specific function of Engrailed-2 in the progression of chronic myelogenous leukemia to T cell blast crisis
Cell Cycle, Vol. 13, Núm. 11, pp. 1717-1726
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Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma
Nature Communications, Vol. 5
2013
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Back to the beginning: The initiation of cancer
BioEssays, Vol. 35, Núm. 5, pp. 413-413
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Function of oncogenes in cancer development: A changing paradigm
EMBO Journal, Vol. 32, Núm. 11, pp. 1502-1513
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Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation
Nature Communications, Vol. 4
2012
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A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors
EMBO Journal, Vol. 31, Núm. 18, pp. 3704-3717
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Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice
Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 26, pp. 10534-10539