Publicaciones en colaboración con investigadores/as de Universidad de Salamanca (75)

2024

  1. Nuclear functions regulated by the VRK1 kinase

    Nucleus, Vol. 15, Núm. 1

  2. Pathogenic effects of Leu200Pro and Arg387His VRK1 protein variants on phosphorylation targets and H4K16 acetylation in distal hereditary motor neuropathy

    Journal of Molecular Medicine, Vol. 102, Núm. 6, pp. 801-817

  3. VRK1 Regulates Sensitivity to Oxidative Stress by Altering Histone Epigenetic Modifications and the Nuclear Phosphoproteome in Tumor Cells

    International Journal of Molecular Sciences, Vol. 25, Núm. 9

2023

  1. VRK1 Kinase Activity Modulating Histone H4K16 Acetylation Inhibited by SIRT2 and VRK-IN-1

    International Journal of Molecular Sciences, Vol. 24, Núm. 5

2022

  1. Targeting Histone Epigenetic Modifications and DNA Damage Responses in Synthetic Lethality Strategies in Cancer?

    Cancers, Vol. 14, Núm. 16

  2. The VRK1 chromatin kinase regulates the acetyltransferase activity of Tip60/KAT5 by sequential phosphorylations in response to DNA damage

    Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, Vol. 1865, Núm. 8

2021

  1. Dysfunctional Homozygous VRK1-D263G Variant Impairs the Assembly of Cajal Bodies and DNA Damage Response in Hereditary Spastic Paraplegia

    Neurology: Genetics, Vol. 7, Núm. 5

  2. Lysine Methyltransferase Inhibitors Impair H4K20me2 and 53BP1 Foci in Response to DNA Damage in Sarcomas, a Synthetic Lethality Strategy

    Frontiers in Cell and Developmental Biology, Vol. 9

  3. Pathogenic convergence of CNVs in genes functionally associated to a severe neuromotor developmental delay syndrome

    Human Genomics, Vol. 15, Núm. 1

  4. VRK1 Depletion Facilitates the Synthetic Lethality of Temozolomide and Olaparib in Glioblastoma Cells

    Frontiers in Cell and Developmental Biology, Vol. 9

2020

  1. Novel dominant kcnq2 exon 7 partial in-frame duplication in a complex epileptic and neurodevelopmental delay syndrome

    International Journal of Molecular Sciences, Vol. 21, Núm. 12, pp. 1-11

  2. VRK1 (Y213H) homozygous mutant impairs Cajal bodies in a hereditary case of distal motor neuropathy

    Annals of Clinical and Translational Neurology, Vol. 7, Núm. 5, pp. 808-818

  3. Vrk1 phosphorylates tip60/kat5 and is required for h4k16 acetylation in response to dna damage

    Cancers, Vol. 12, Núm. 10, pp. 1-24

2019

  1. Olaparib and ionizing radiation trigger a cooperative DNA-damage repair response that is impaired by depletion of the VRK1 chromatin kinase

    Journal of Experimental and Clinical Cancer Research, Vol. 38, Núm. 1

2018

  1. Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?

    Cellular and Molecular Life Sciences, Vol. 75, Núm. 13, pp. 2375-2388

  2. VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis

    Cellular and Molecular Life Sciences, Vol. 75, Núm. 14, pp. 2591-2611

2017

  1. Is Centrosomal Protein 70, a Centrosomal Protein with New Roles in Breast Cancer Dissemination and Metastasis, a Facilitator of Epithelial-Mesenchymal Transition?

    American Journal of Pathology, Vol. 187, Núm. 3, pp. 494-497

  2. Reverting p53 activation after recovery of cellular stress to resume with cell cycle progression

    Cellular Signalling, Vol. 33, pp. 49-58

2016

  1. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Autophagy

  2. Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

    Oncogene, Vol. 35, Núm. 33, pp. 4407-4413