Química
Disciplina temática
Centro de Investigaciones Biológicas
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigaciones Biológicas (16)
2023
-
Plastic degradation by insect hexamerins: Near-atomic resolution structures of the polyethylene-degrading proteins from the wax worm saliva
Science advances, Vol. 9, Núm. 38, pp. eadi6813
2022
-
Wax worm saliva and the enzymes therein are the key to polyethylene degradation by Galleria mellonella
Nature Communications, Vol. 13, Núm. 1
2021
-
Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents
European Journal of Medicinal Chemistry, Vol. 209
-
New diarylsulfonamide inhibitors of Leishmania infantum amastigotes
International Journal for Parasitology: Drugs and Drug Resistance, Vol. 16, pp. 45-64
-
New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure–activity relationships, and molecular modelling
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 2025-2044
2020
2019
-
Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target
Medicinal Research Reviews, Vol. 39, Núm. 3, pp. 775-830
-
Imidazo[2,1-a]isoindole scaffold as an uncharted structure active on Leishmania donovani
European Journal of Medicinal Chemistry, Vol. 182
-
The Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors
Molecules (Basel, Switzerland), Vol. 24, Núm. 23
2018
-
Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells
European Journal of Medicinal Chemistry, Vol. 158, pp. 167-183
2016
-
Synthesis of bioconjugate sesterterpenoids with phospholipids and polyunsaturated fatty acids
Molecules, Vol. 21, Núm. 1
2015
-
Mechanisms of action of substituted β-amino alkanols on leishmania donovani
Antimicrobial Agents and Chemotherapy, Vol. 59, Núm. 2, pp. 1211-1218
2014
-
The Acinetobacter baumannii Omp33-36 porin is a virulence factor that induces apoptosis and modulates autophagy in human cells
Infection and Immunity, Vol. 82, Núm. 11, pp. 4666-4680
2013
-
Endowing indole-based tubulin inhibitors with an anchor for derivatization: Highly potent 3-substituted indolephenstatins and indoleisocombretastatins
Journal of Medicinal Chemistry, Vol. 56, Núm. 7, pp. 2813-2827
2012
-
Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins
Journal of Medicinal Chemistry, Vol. 55, Núm. 15, pp. 6724-6737
2000
-
Design, synthesis and cytotoxic activities of naphthyl analogues of combretastatin A-4
Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 22, pp. 2549-2551