Enfoque terapéutico interdisciplinar de la epilepsia refractaria.

  1. Patricia García Lucas 1
  2. Gloria Cucalón Leciñena 2
  3. Eva Monge Pelegrín 1
  4. María Ángeles Val Lorente 1
  5. María Egea Auría 3
  6. Silvia Gran Embid 4
  1. 1 Hospital Universitario Miguel Servet (Zaragoza, España).
  2. 2 Hospital Clínico Lozano Blesa (Zaragoza, España).
  3. 3 Centro de Atención Primaria Parque Goya (Zaragoza, España).
  4. 4 Centro de Atención Primaria José Ramón Muñoz Fernández (Zaragoza, España).
Revista:
Revista Sanitaria de Investigación

ISSN: 2660-7085

Any de publicació: 2021

Volum: 2

Número: 2

Tipus: Article

Altres publicacions en: Revista Sanitaria de Investigación

Resum

Introduction: Epilepsy is a neurological disorder that presents with recurrent seizures. Although the treatment of choice is pharmacological, there are cases of ineffective response to it. In refractory epilepsy with an ineffective response to pharmacological treatment, the ketogenic diet can be considered as adjunctive treatment. The ketogenic diet is characterized by providing most of the caloric percentage through lipids, which implies an alteration of the physiological metabolism depending on the energy needs of the individual. Method: In this article the evaluation of the existing bibliography regarding the effectiveness of the ketogenic diet as part of the therapeutic approach to refractory epilepsy is proposed. Discussion: There is heterogeneity in the consulted scientific literature. However, the authors agree that the ketogenic diet implies a change in the source of energy used for metabolism, which is mostly fat. The use of fats as a source of metabolic energy can lead to adverse effects for the body, so it must be individualized and controlled over time, according to the energy needs required by the individual. Conclusion: Although the scientific literature does not reflect strong scientific evidence in this regard, the ketogenic diet could be considered as a feasible option for refractory epilepsy as an adjunctive treatment for remission of seizure status.