Eugenio Miguel
Santos de Dios
National Cancer Institute
Rockville, Estados UnidosPublicaciones en colaboración con investigadores/as de National Cancer Institute (34)
2013
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Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival
Molecular and Cellular Biology, Vol. 33, Núm. 22, pp. 4562-4578
2000
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The Sos1 and Sos2 Ras-specific exchange factors: Differences in placental expression and signaling properties
EMBO Journal, Vol. 19, Núm. 4, pp. 642-654
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The isoform-specific stretch of hSos1 defines a new Grb2-binding domain
Oncogene, Vol. 19, Núm. 51, pp. 5872-5883
1999
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Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1
Oncogene, Vol. 18, Núm. 9, pp. 1651-1661
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Oncogenic Ras-induced germinal vesicle breakdown is independent of phosphatidylinositol 3-kinase in Xenopus oocytes
FEBS Letters, Vol. 451, Núm. 3, pp. 284-288
1998
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Transformation suppressor activity of C3G is independent of its CDC25-homology domain
Oncogene, Vol. 16, Núm. 5, pp. 613-624
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Transforming G protein-coupled receptors block insulin and ras-induced adipocytic differentiation in 3T3-L1 cells: Evidence for a PKC and MAP kinase independent pathway
Biochemical and Biophysical Research Communications, Vol. 245, Núm. 2, pp. 554-561
1997
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Biological activity of p27(kip1) and its amino- and carboxy-terminal domains in G2/M transition of Xenopus oocytes
Oncogene, Vol. 15, Núm. 21, pp. 2541-2551
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Carboxyl-terminal domain of p27(Kip1) activates CDC2
Journal of Biological Chemistry, Vol. 272, Núm. 35, pp. 21669-21672
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Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation
Molecular and Cellular Biology, Vol. 17, Núm. 10, pp. 6068-6075
1996
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A 15 amino acid stretch close to the Grb2-binding domain defines two differentially expressed hSos1 isoforms with markedly different Grb2 binding affinity and biological activity
Oncogene, Vol. 12, Núm. 11, pp. 2291-2300
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Expression of alternative forms of Ras exchange factors GRF and SOS1 in different human tissues and cell lines
Oncogene, Vol. 12, Núm. 5, pp. 1097-1107
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Functional interactions between isolated SH2 domains and insulin/Ras signaling pathways of Xenopus oocytes: Opposite effects of the carboxy- and amino-terminal SH2 domains of p85 PI 3-kinase
Oncogene, Vol. 13, Núm. 9, pp. 1839-1846
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Isolated Sos1 PH domain exhibits germinal vesicle breakdown-inducing activity in Xenopus oocytes
Journal of Biological Chemistry, Vol. 271, Núm. 30, pp. 18272-18276
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The insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells: Dissociation between Raf-1 kinase and the MAPK/RSK cascade
International Journal of Obesity
1995
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A Divalent Metal Ion Binding Site in the Kinase Insert Domain of the α-Platelet-Derived Growth Factor Receptor Regulates Its Association with SH2 Domains
Biochemistry, Vol. 34, Núm. 7, pp. 2095-2106
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Human dual specificity phosphatase VHR activates maturation promotion factor and triggers meiotic maturation in Xenopus oocytes
Journal of Biological Chemistry, Vol. 270, Núm. 23, pp. 14229-14234
1994
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An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: Evidence for a ret-specific signaling pathway
Molecular and Cellular Biology, Vol. 14, Núm. 1, pp. 663-675
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Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen- activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells
Journal of Biological Chemistry, Vol. 269, Núm. 17, pp. 12741-12748