XOSE R.
Garcia Bustelo
Publicacions (175) Publicacions de XOSE R. Garcia Bustelo
2024
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The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis
Molecular Oncology
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Unmutated RRAS2 emerges as a key oncogene in post-partum-associated triple negative breast cancer
Molecular Cancer, Vol. 23, Núm. 1
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VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma
Scientific Reports, Vol. 14, Núm. 1
2023
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An Optimized Single Nucleotide Polymorphism-Based Detection Method Suggests That Allelic Variants in the 3’ Untranslated Region of RRAS2 Correlate with Treatment Response in Chronic Lymphocytic Leukemia Patients
Cancers, Vol. 15, Núm. 3
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Characterization of Three Somatic Mutations in the 3′UTR of RRAS2 and Their Inverse Correlation with Lymphocytosis in Chronic Lymphocytic Leukemia
Cells, Vol. 12, Núm. 23
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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors
Oncogene, Vol. 42, Núm. 5, pp. 389-405
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Investigación cooperativa en cáncer: El centro de investigación del cáncer de Salamanca
Encuentros multidisciplinares, Vol. 25, Núm. 75
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Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies
Cancers, Vol. 15, Núm. 24
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Scaffold coupling: ERK activation by transphosphorylation across different scaffold protein species
Science Advances, Vol. 9, Núm. 7
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The Rho GTPase exchange factor Vav2 promotes extensive age-dependent rewiring of the hair follicle stem cell transcriptome
Frontiers in Cell and Developmental Biology, Vol. 11
2022
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A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
Cell Reports, Vol. 38, Núm. 11
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Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model
Molecular Oncology, Vol. 16, Núm. 19, pp. 3533-3553
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CiberAMP: An R Package to Identify Differential mRNA Expression Linked to Somatic Copy Number Variations in Cancer Datasets
Biology, Vol. 11, Núm. 10
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Hematopoietic Cells Influence Vascular Development in the Retina
Cells, Vol. 11, Núm. 20
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Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis
Nature Communications, Vol. 13, Núm. 1
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Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia
Molecular Cancer, Vol. 21, Núm. 1
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The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Oncogene, Vol. 41, Núm. 24, pp. 3341-3354
2021
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Aryl hydrocarbon receptor controls skin homeostasis, regeneration, and hair follicle cycling by adjusting epidermal stem cell function
Stem Cells, Vol. 39, Núm. 12, pp. 1733-1750
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Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis
EMBO Journal, Vol. 40, Núm. 22
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Distinct roles of vav family members in adaptive and innate immune models of arthritis
Biomedicines, Vol. 9, Núm. 6