Publications (175) Publications de XOSE R. Garcia Bustelo

2024

  1. The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis

    Molecular Oncology

  2. Unmutated RRAS2 emerges as a key oncogene in post-partum-associated triple negative breast cancer

    Molecular Cancer, Vol. 23, Núm. 1

  3. VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma

    Scientific Reports, Vol. 14, Núm. 1

2023

  1. An Optimized Single Nucleotide Polymorphism-Based Detection Method Suggests That Allelic Variants in the 3’ Untranslated Region of RRAS2 Correlate with Treatment Response in Chronic Lymphocytic Leukemia Patients

    Cancers, Vol. 15, Núm. 3

  2. Characterization of Three Somatic Mutations in the 3′UTR of RRAS2 and Their Inverse Correlation with Lymphocytosis in Chronic Lymphocytic Leukemia

    Cells, Vol. 12, Núm. 23

  3. Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors

    Oncogene, Vol. 42, Núm. 5, pp. 389-405

  4. Investigación cooperativa en cáncer: El centro de investigación del cáncer de Salamanca

    Encuentros multidisciplinares, Vol. 25, Núm. 75

  5. Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies

    Cancers, Vol. 15, Núm. 24

  6. Scaffold coupling: ERK activation by transphosphorylation across different scaffold protein species

    Science Advances, Vol. 9, Núm. 7

  7. The Rho GTPase exchange factor Vav2 promotes extensive age-dependent rewiring of the hair follicle stem cell transcriptome

    Frontiers in Cell and Developmental Biology, Vol. 11

2022

  1. A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors

    Cell Reports, Vol. 38, Núm. 11

  2. Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model

    Molecular Oncology, Vol. 16, Núm. 19, pp. 3533-3553

  3. CiberAMP: An R Package to Identify Differential mRNA Expression Linked to Somatic Copy Number Variations in Cancer Datasets

    Biology, Vol. 11, Núm. 10

  4. Hematopoietic Cells Influence Vascular Development in the Retina

    Cells, Vol. 11, Núm. 20

  5. Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis

    Nature Communications, Vol. 13, Núm. 1

  6. Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia

    Molecular Cancer, Vol. 21, Núm. 1

  7. The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function

    Oncogene, Vol. 41, Núm. 24, pp. 3341-3354

2021

  1. Aryl hydrocarbon receptor controls skin homeostasis, regeneration, and hair follicle cycling by adjusting epidermal stem cell function

    Stem Cells, Vol. 39, Núm. 12, pp. 1733-1750

  2. Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis

    EMBO Journal, Vol. 40, Núm. 22

  3. Distinct roles of vav family members in adaptive and innate immune models of arthritis

    Biomedicines, Vol. 9, Núm. 6